null

PURB Rabbit Polyclonal Antibody (CAB18166)

SKU:
CAB18166
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:PURB Rabbit Polyclonal Antibody
SKU:CAB18166
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 213-312 of human PURB (NP_150093.1).
Sequence:GGLY GELP EGTS ITVD SKRF FFDV GCNK YGVF LRVS EVKP SYRN AITV PFKA WGKF GGAF CRYA DEMK EIQE RQRD KLYE RRGG GSGG GEES EGEE VDED
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:PURBETA; PURB
Positive Sample:LO2,HeLa
Cellular Localization:nucleoplasm, nucleus
Calculated MW:33kDa
Observed MW:38kDa

This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia.

Purification Method:Affinity purification
Gene ID:5814
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using PURB Rabbit pAb (CAB18166) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.

Related Products