Pumilio 1 Rabbit Polyclonal Antibody (CAB13389)
- SKU:
- CAB13389
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Description
Product Name: | Pumilio 1 Rabbit Polyclonal Antibody |
SKU: | CAB13389 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human Pumilio 1 (NP_055491.1). |
Sequence: | MSVA CVLK RKAV LWQD SFSP HLKH HPQE PANP NMPV VLTS GTGS QAQP QPAA NQAL AAGT HSSP VPGS IGVA GRSQ DDAM VDYF FQRQ HGEQ LGGG GSGG GGYN NSKH RWPT GDNI HAEH QVRS MDEL NH |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | PUMH; HSPUM; PUMH1; PUML1; SCA47; Pumilio 1 |
Positive Sample: | HepG2,SH-SY5Y,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Cytoplasmic granule, P-body. |
Calculated MW: | 126kDa |
Observed MW: | 126kDa |
This gene encodes a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. The encoded protein contains a sequence-specific RNA binding domain comprised of eight repeats and N- and C-terminal flanking regions, and serves as a translational regulator of specific mRNAs by binding to their 3' untranslated regions. The evolutionarily conserved function of the encoded protein in invertebrates and lower vertebrates suggests that the human protein may be involved in translational regulation of embryogenesis, and cell development and differentiation. Alternatively spliced transcript variants encoding different isoforms have been described.
Purification Method: | Affinity purification |
Gene ID: | 9698 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |