PUF60 Rabbit Polyclonal Antibody (CAB6709)
- SKU:
- CAB6709
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | PUF60 Rabbit Polyclonal Antibody |
SKU: | CAB6709 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 243-542 of human PUF60 (NP_055096.2). |
Sequence: | DPTT GKHK GYGF IEYE KAQS SQDA VSSM NLFD LGGQ YLRV GKAV TPPM PLLT PATP GGLP PAAA VAAA AATA KITA QEAV AGAA VLGT LGTP GLVS PALT LAQP LGTL PQAV MAAQ APGV ITGV TPAR PPIP VTIP SVGV VNPI LASP PTLG LLEP KKEK EEEE LFPE SERP EMLS EQEH MSIS GSSA RHMV MQKL LRKQ ESTV MVLR NMVD PKDI DDDL EGEV TEEC GKFG AVNR VIIY QEKQ GEEE DAEI IVKI FVEF SIAS ETHK AIQA LNGR WFAG RKVV AEVY DQER FDNS DLSA |
Tested Applications: | WB IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | FIR; VRJS; RoBPI; SIAHBP1; PUF60 |
Positive Sample: | THP-1,A-549,Mouse brain,Mouse thymus,Mouse spleen,Rat lung,Rat liver,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 60kDa |
Observed MW: | 65kDa |
This gene encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. The encoded protein forms a complex with the far upstream DNA element (FUSE) and FUSE-binding protein at the myelocytomatosis oncogene (MYC) promoter. This complex represses MYC transcription through the core-TFIIH basal transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method: | Affinity purification |
Gene ID: | 22827 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |