The PTX3 Polyclonal Antibody (CAB12669) is a valuable tool for researchers studying PTX3, a multifunctional protein involved in inflammation and immune response. This antibody, produced in rabbits, is highly specific to PTX3 and has been validated for use in a variety of applications including Western blot and immunohistochemistry.PTX3, also known as pentraxin-related protein PTX3, is a key player in the innate immune response and has been implicated in various inflammatory diseases and conditions.
By targeting PTX3 with this antibody, researchers can investigate its role in conditions such as infections, cardiovascular diseases, and autoimmune disorders.With its high reactivity and specificity for PTX3, this polyclonal antibody is an essential tool for researchers looking to better understand the functions and mechanisms of PTX3 in health and disease. Its versatility in application makes it suitable for a wide range of experiments in immunology, inflammation, and related fields.
Product Name:
PTX3 Rabbit Polyclonal Antibody
SKU:
CAB12669
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 18-381 of human PTX3 (NP_002843.2).
This gene encodes a member of the pentraxin protein family. The expression of this protein is induced by inflammatory cytokines in response to inflammatory stimuli in several mesenchymal and epithelial cell types, particularly endothelial cells and mononuclear phagocytes. The protein promotes fibrocyte differentiation and is involved in regulating inflammation and complement activation. It also plays a role in angiogenesis and tissue remodeling. The protein serves as a biomarker for several inflammatory conditions.
Purification Method:
Affinity purification
Gene ID:
5806
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PTX3 Rabbit pAb (CAB12669) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
