The PTTG2 Polyclonal Antibody (PACO58540) is a valuable tool for researchers studying PTTG2, a protein involved in cell division and tumor development. This antibody, generated in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications. By binding to the PTTG2 protein, researchers can accurately detect and analyze its expression in various cell types, making it an essential tool for studies in cancer biology and cell cycle regulation.PTTG2, also known as pituitary tumor-transforming gene 2, plays a crucial role in regulating cell division and promoting tumor growth.
Understanding the function and expression of PTTG2 is essential for unraveling its role in tumorigenesis and identifying potential therapeutic targets for cancer treatment. With its ability to detect PTTG2 in different cell types, this antibody is a valuable resource for researchers investigating the molecular mechanisms underlying cancer development and progression.
Immunofluorescence staining of PC-3 cells with PACO58540 at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
nucleus, peptidase inhibitor activity, homologous chromosome segregation, negative regulation of mitotic sister chromatid separation, regulation of transcription, DNA-templated
