The PTS Polyclonal Antibody (CAB6306) is a specialized research tool designed for the study of PTS, a cell surface molecule with implications in immune response regulation. This antibody, produced through rabbit immunization, exhibits high reactivity towards human samples and has been validated for Western blot applications. By binding specifically to the PTS protein, researchers can effectively detect and analyze its presence in diverse cell types, making it an invaluable asset for studies within the fields of immunology and cancer research.
PTS, known for its role as an immune regulatory receptor, holds great significance in maintaining immune balance by moderating inflammation and suppressing allergic responses. Its involvement in immune modulation positions it as a promising target for investigations into diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. Insight into the functions of PTS is crucial for the development of therapeutic approaches that leverage or regulate immune activity in these disease settings.
Product Name:
PTS Rabbit Polyclonal Antibody
SKU:
CAB6306
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-145 of human PTS (NP_000308.1).
The enzyme encoded by this gene catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia.
Purification Method:
Affinity purification
Gene ID:
5805
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PTS antibody (CAB6306) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
