PTPRR Rabbit Polyclonal Antibody (CAB12246)
- SKU:
- CAB12246
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PTPRR Rabbit Polyclonal Antibody |
SKU: | CAB12246 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-227 of human PTPRR (NP_002840.2). |
Sequence: | FSGN NDHF LAIN QKKS GKPV FIYK HSQD IEKS LDIA PQKI YRHS YHSS SEAQ VSKR HQIV NSAF PRPA YDPS LNLL AMDG QDLE VENL PIPA ANVI VVTL QMDV NKLN ITLL RIFR QGVA AALG LLPQ QVHI NRLI GKKN SIEL FVSP INRK TGIS DALP SEEV LRSL NINV LHQS LSQF GITE VSPE KNVL QGQH EADK IWSK EG |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | PTPRQ; EC-PTP; PCPTP1; PTP-SL; PTPBR7; PTPRR |
Positive Sample: | U-87MG,HT-29,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Single-pass type I membrane protein, perinuclear region, perinuclear region. |
Calculated MW: | 74kDa |
Observed MW: | 50kDa |
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. Silencing of this gene has been associated with colorectal cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares a symbol (PTPRQ) with another gene, protein tyrosine phosphatase, receptor type, Q (GeneID 374462), which is also located on chromosome 12.
Purification Method: | Affinity purification |
Gene ID: | 5801 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |