PTPRO Rabbit Polyclonal Antibody (CAB6958)
- SKU:
- CAB6958
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PTPRO Rabbit Polyclonal Antibody |
SKU: | CAB6958 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-300 of human PTPRO (NP_109592.1). |
Sequence: | FHVT VQDD NNIV VSLE ASDV ISPA SVYV VKIT GESK NYFF EFEE FNST LPPP VIFK ASYH GLYY IITL VVVN GNVV TKPS RSIT VLTK PLPV TSVS IYDY KPSP ETGV LFEI HYPE KYNV FTRV NISY WEGK DFRT MLYK DFFK GKTV FNHW LPGM CYSN ITFQ LVSE ATFN KSTL VEYS GVSH EPKQ HRTA PYPP QNIS VRIV NLNK NNWE EQSG NFPE ESFM RSQD TIGK EKLF HFTE ETPE IPSG NISS GWPD FNSS DYET TSQP YWW |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | NPHS6; PTPU2; GLEPP1; PTP-OC; PTP-U2; PTPROT; R-PTP-O; PTPRO |
Positive Sample: | Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 138kDa |
Observed MW: | 138kDa |
This gene encodes a member of the R3 subtype family of receptor-type protein tyrosine phosphatases. These proteins are localized to the apical surface of polarized cells and may have tissue-specific functions through activation of Src family kinases. This gene contains two distinct promoters, and alternatively spliced transcript variants encoding multiple isoforms have been observed. The encoded proteins may have multiple isoform-specific and tissue-specific functions, including the regulation of osteoclast production and activity, inhibition of cell proliferation and facilitation of apoptosis. This gene is a candidate tumor suppressor, and decreased expression of this gene has been observed in several types of cancer.
Purification Method: | Affinity purification |
Gene ID: | 5800 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |