PTPRN2 Rabbit Polyclonal Antibody (CAB14774)
- SKU:
- CAB14774
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | PTPRN2 Rabbit Polyclonal Antibody |
SKU: | CAB14774 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-242 of human PTPRN2 (NP_570858.2). |
Sequence: | AAPS SVPR GRQL PGRL GCLL EEGL CGAS EACV NDGV FGRC QKVP AMDF YRYE VSPV ALQR LRVA LQKL SGTG FTWQ DDYT QYVM DQEL ADLP KTYL RRPE ASSP ARPS KHSV GSER RYSR EGGA ALAN ALRR HLPF LEAL SQAP ASDV LART HTAQ DRPP AEGD DRFS ESIL TYVA HTSA LTYP PGSR TQLR EDLL PRTL GQLQ PDEL SPKV DSGV DRHH L |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:100 |
Synonyms: | IAR; ICAAR; PTPRP; IA-2beta; R-PTP-N2; PTPRN2 |
Positive Sample: | SH-SY5Y,SGC-7901,Mouse pancreas,Rat pancreas |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasmic vesicle, Single-pass type I membrane protein, secretory vesicle, secretory vesicle membrane, synaptic vesicle membrane. |
Calculated MW: | 111kDa |
Observed MW: | 111kDa |
This gene encodes a protein with sequence similarity to receptor-like protein tyrosine phosphatases. However, tyrosine phosphatase activity has not been experimentally validated for this protein. Studies of the rat ortholog suggest that the encoded protein may instead function as a phosphatidylinositol phosphatase with the ability to dephosphorylate phosphatidylinositol 3-phosphate and phosphatidylinositol 4,5-diphosphate, and this function may be involved in the regulation of insulin secretion. This protein has been identified as an autoantigen in insulin-dependent diabetes mellitus. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 5799 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |