PTPRN Rabbit Polyclonal Antibody (CAB6401)
- SKU:
- CAB6401
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | PTPRN Rabbit Polyclonal Antibody |
SKU: | CAB6401 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 600-889 of human PTPRN (NP_001186693.1). |
Sequence: | STGH MILA YMED HLRN RDRL AKEW QALC AYQA EPNT CATA QGEG NIKK NRHP DFLP YDHA RIKL KVES SPSR SDYI NASP IIEH DPRM PAYI ATQG PLSH TIAD FWQM VWES GCTV IVML TPLV EDGV KQCD RYWP DEGA SLYH VYEV NLVS EHIW CEDF LVRS FYLK NVQT QETR TLTQ FHFL SWPA EGTP ASTR PLLD FRRK VNKC YRGR SCPI IVHC SDGA GRTG TYIL IDMV LNRM AKGV KEID IAAT LEHV RDQR PGLV RSKD QFEF ALTA VAEE VNAI LKAL PQ |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | IA2; IA-2; ICA512; R-PTP-N; IA-2/PTP; PTPRN |
Positive Sample: | 293T,NIH/3T3,Raji,Mouse brain,Rat brian |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Cell projection, Cytoplasmic vesicle, Endosome, Membrane, Perikaryon, Single-pass type I membrane protein, axon, secretory vesicle membrane, synapse. |
Calculated MW: | 106kDa |
Observed MW: | 66kDa |
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 5798 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |