PTPRG Rabbit Polyclonal Antibody (CAB14253)
- SKU:
- CAB14253
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | PTPRG Rabbit Polyclonal Antibody |
SKU: | CAB14253 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 250-450 of human PTPRG (NP_002832.3). |
Sequence: | YRYT GSLT TPPC SEIV EWIV FRRP VPIS YHQL EAFY SIFT TEQQ DHVK SVEY LRNN FRPQ QRLH DRVV SKSA VRDS WNHD MTDF LENP LGTE ASKV CSSP PIHM KVQP LNQT ALQV SWSQ PETI YHPP IMNY MISY SWTK NEDE KEKT FTKD SDKD LKAT ISHV SPDS LYLF RVQA VCRN DMRS DFSQ TMLF QANT TRIF Q |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | PTPG; HPTPG; RPTPG; R-PTP-GAMMA; PTPRG |
Positive Sample: | A-549,293T,Mouse kidney,Mouse heart,Mouse liver,Rat spleen |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 162kDa |
Observed MW: | 140-162kDa |
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene.
Purification Method: | Affinity purification |
Gene ID: | 5793 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |