PTPRE Rabbit Polyclonal Antibody (CAB7209)
- SKU:
- CAB7209
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | PTPRE Rabbit Polyclonal Antibody |
SKU: | CAB7209 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-200 of human PTPRE (NP_006495.1). |
Sequence: | LRGN ETTA DSNE TTTT SGPP DPGA SQPL LAWL LLPL LLLL LVLL LAAY FFRF RKQR KAVV STSD KKMP NGIL EEQE QQRV MLLS RSPS GPKK YFPI PVEH LEEE IRIR SADD CKQF REEF NSLP SGHI QGTF ELAN KEEN REKN RYPN ILPN DHSR VILS QLDG IPCS DYIN ASYI DGYK E |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | PTPE; HPTPE; R-PTP-EPSILON; PTPRE |
Positive Sample: | HL-60,SW620,Mouse brain,Mouse spleen,Mouse lung,Rat brain,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Cytoplasm, Single-pass type I membrane protein. |
Calculated MW: | 81kDa |
Observed MW: | 81kDa |
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Several alternatively spliced transcript variants of this gene have been reported, at least two of which encode a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokine-induced SATA signaling, as well as the activation of voltage-gated K+ channels.
Purification Method: | Affinity purification |
Gene ID: | 5791 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |