The PTPRD Polyclonal Antibody (CAB8559) is a key tool for researchers studying the protein tyrosine phosphatase receptor type D (PTPRD), which plays a crucial role in various cellular processes including cell growth, differentiation, and immune response. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it an ideal choice for Western blot applications.PTPRD is known to be involved in regulating signaling pathways related to growth factor receptors and immune responses, making it a potential target for therapeutic interventions in diseases such as cancer and autoimmune disorders.
By specifically binding to PTPRD, this antibody enables accurate detection and analysis of the protein in various cell types, facilitating research in immunology and cancer biology.By utilizing the PTPRD Polyclonal Antibody, researchers can gain valuable insights into the role of PTPRD in disease development and progression, paving the way for the development of targeted therapies that aim to modulate its activity for therapeutic benefit. This antibody is a valuable tool for scientists seeking to deepen their understanding of the molecular mechanisms underlying various disease states and explore new avenues for treatment.
Product Name:
PTPRD Rabbit Polyclonal Antibody
SKU:
CAB8559
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 475-574 of human PTPRD (NP_002830.1).
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple alternatively spliced transcript variants of this gene have been reported. A related pseudogene has been identified on chromosome 5.
Purification Method:
Affinity purification
Gene ID:
5789
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using PTPRD Rabbit pAb (CAB8559) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
