The PTPRD Polyclonal Antibody (CAB15713) is a valuable tool for researchers studying the PTPRD protein, a tyrosine phosphatase receptor involved in various cellular processes including cell growth, differentiation, and immune regulation. This antibody, generated in rabbits, exhibits high specificity and reactivity towards human samples, making it an ideal choice for Western blot applications.PTPRD, also known as protein tyrosine phosphatase receptor type D, is a key player in signal transduction pathways that regulate cell proliferation and differentiation.
Dysregulation of PTPRD has been implicated in cancer development, making it a promising target for therapeutic interventions. By detecting and analyzing PTPRD expression in different cell types, this antibody facilitates research in oncology and molecular biology, providing insights into the role of PTPRD in disease progression and therapeutic resistance.
Product Name:
PTPRD Rabbit Polyclonal Antibody
SKU:
CAB15713
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1100-1265 of human PTPRD (NP_002830.1).
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple alternatively spliced transcript variants of this gene have been reported. A related pseudogene has been identified on chromosome 5.
Purification Method:
Affinity purification
Gene ID:
5789
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PTPRD Rabbit pAb (CAB15713) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
