PTPRA Rabbit Polyclonal Antibody (CAB1976)
- SKU:
- CAB1976
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PTPRA Rabbit Polyclonal Antibody |
SKU: | CAB1976 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-142 of human PTPRA (NP_543031.1). |
Sequence: | NNAT TVAP SVGI TRLI NSST AEPV KEEA KTSN PTSS LTSL SVAP TFSP NITL GPTY LTTV NSSD SDNG TTRT ASTN SIGI TISP NGTW LPDN QFTD ARTE PWEG NSST AATT PETF PPSD ETP |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:100 - 1:200 |
Synonyms: | LRP; HLPR; PTPA; HEPTP; HPTPA; RPTPA; PTPRL2; HPTPalpha; R-PTP-alpha; PTPRA |
Positive Sample: | SW620,22Rv1,BT-474,Mouse brain,Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 91kDa |
Observed MW: | 120kDa |
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported.
Purification Method: | Affinity purification |
Gene ID: | 5786 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |