The PTPN5 Polyclonal Antibody (CAB16585) is a vital tool for research involving PTPN5, a protein tyrosine phosphatase implicated in various cellular processes, including cell growth, differentiation, and immune response regulation. This antibody, produced in rabbits, exhibits strong reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the PTPN5 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an excellent choice for studies in immunology, cancer research, and beyond.
PTPN5, also known as STEP (Striatal-Enriched Protein Tyrosine Phosphatase), plays a crucial role in regulating signaling pathways that control neuronal function and synaptic plasticity in the brain. Its involvement in modulating cell signaling cascades makes PTPN5 a promising target for research exploring neurological disorders, cognitive function, and neurodegenerative diseases. By elucidating the mechanisms by which PTPN5 influences cellular processes, researchers can gain valuable insights into potential therapeutic strategies for treating these conditions.
Product Name:
PTPN5 Rabbit Polyclonal Antibody
SKU:
CAB16585
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 190-307 of human PTPN5 (NP_116170.3).
Enables phosphotyrosine residue binding activity. Predicted to be involved in peptidyl-tyrosine dephosphorylation. Predicted to act upstream of or within protein dephosphorylation. Predicted to be located in nucleoplasm. Predicted to be integral component of membrane. Biomarker of Alzheimer's disease.
Purification Method:
Affinity purification
Gene ID:
84867
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PTPN5 antibody (CAB16585) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
