The PTPN4 Polyclonal Antibody (CAB4061) is a valuable tool for researchers studying the PTPN4 protein, also known as Protein Tyrosine Phosphatase Non-Receptor Type 4. PTPN4 is involved in various cellular processes, including cell growth, differentiation, and immune response modulation. This antibody, derived from rabbits, exhibits high reactivity with PTPN4 in human samples and has been validated for use in Western blot applications. By binding specifically to PTPN4, this antibody allows for accurate detection and analysis of the protein in a variety of cell types, making it suitable for research in areas such as immunology and cancer biology.
PTPN4 plays a crucial role in regulating signaling pathways involved in cell proliferation and differentiation, making it a promising target for therapeutic interventions in conditions like cancer and autoimmune disorders. By investigating the function of PTPN4 using this antibody, researchers can gain valuable insights into the mechanisms underlying disease development and potentially identify new treatment strategies.
Product Name:
PTPN4 Rabbit Polyclonal Antibody
SKU:
CAB4061
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human PTPN4 (NP_002821.1).
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. This PTP has been shown to interact with glutamate receptor delta 2 and epsilon subunits, and is thought to play a role in signalling downstream of the glutamate receptors through tyrosine dephosphorylation.
Purification Method:
Affinity purification
Gene ID:
5775
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PTPN4 antibody (CAB4061) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
