PTPN3 Rabbit Polyclonal Antibody (CAB6400)
- SKU:
- CAB6400
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PTPN3 Rabbit Polyclonal Antibody |
SKU: | CAB6400 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PTPN3 (NP_001138840.1). |
Sequence: | MTSR LRAL GGRI NNIR TSEL PKEK TRSE VICS IHFL DGVV QTFK VTKQ DTGQ VLLD MVHN HLGV TEKE YFGL QHDD DSVD SPRW LEAS KAIR KQLK GGFP CTLH FRVR FFIP DPNT LQQE QTRH LYFL QLKM DICE GRLT CPLN SAVV LASY AVQS HFGD YNSS IHHP GYLS DSHF IPDQ NEDF LTKV ESLH EQHS GLKQ SEAE SCYI NIAR TLDF YGVE LHSG RDLH NLDL MIGI ASAG VAVY RKYI CTSF YPWV NILK ISFK RKKF FIHQ RQKQ AESR EHIV AFNM LNYR SCKN LWKS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | PTPH1; PTP-H1; PTPN3 |
Positive Sample: | A-549,BT-474,293T,Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Cytoplasmic side, Peripheral membrane protein, cytoskeleton. |
Calculated MW: | 104kDa |
Observed MW: | 103kDa |
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. P97, a cell cycle regulator involved in a variety of membrane related functions, has been shown to be a substrate of this PTP. This PTP was also found to interact with, and be regulated by adaptor protein 14-3-3 beta. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 5774 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |