The PTPN23 Polyclonal Antibody (CAB4595) is a valuable tool for researchers studying PTPN23, a protein tyrosine phosphatase involved in various cellular processes, including cell growth, differentiation, and immune response regulation. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.PTPN23 is a key player in signal transduction pathways, modulating the activity of numerous proteins by removing phosphate groups from tyrosine residues. Dysregulation of PTPN23 has been associated with cancer progression, immune disorders, and metabolic diseases, making it an attractive target for therapeutic interventions.
By targeting PTPN23 with this polyclonal antibody, researchers can detect and analyze the protein in diverse cell types, shedding light on its role in health and disease. This antibody is a valuable tool for studies in oncology, immunology, and cellular signaling pathways, providing insights that may pave the way for novel treatment strategies in various pathological conditions.
Product Name:
PTPN23 Rabbit Polyclonal Antibody
SKU:
CAB4595
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1230-1450 of human PTPN23 (NP_056281.1).
This gene encodes a member of the non-receptor type protein-tyrosine phosphatase family. The encoded protein may be involved in the regulation of small nuclear ribonucleo protein assembly and pre-mRNA splicing by modifying the survival motor neuron (SMN) complex. The encoded protein additionally plays a role in ciliogenesis and is part of endosomal sorting complex required for transport (ESCRT) pathways. This gene may serve a tumor suppressor function.
Purification Method:
Affinity purification
Gene ID:
25930
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using PTPN23 Rabbit pAb (CAB4595) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
