PTPN22 Rabbit Polyclonal Antibody (CAB1406)
- SKU:
- CAB1406
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Autophagy
Frequently bought together:
Description
Product Name: | PTPN22 Rabbit Polyclonal Antibody |
SKU: | CAB1406 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human PTPN22 (NP_036543.4). |
Sequence: | MDQR EILQ KFLD EAQS KKIT KEEF ANEF LKLK RQST KYKA DKTY PTTV AEKP KNIK KNRY KDIL PYDY SRVE LSLI TSDE DSSY INAN FI |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | LYP; PEP; LYP1; LYP2; PTPN8; PTPN22.5; PTPN22.6; PTPN22 |
Positive Sample: | Jurkat,Mouse spleen |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 92kDa |
Observed MW: | 107kDa |
This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Purification Method: | Affinity purification |
Gene ID: | 26191 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |