The PTPMT1 Polyclonal Antibody (CAB8594) is a valuable tool for researchers studying the PTPMT1 protein, a phosphatase involved in regulating mitochondrial function and metabolism. This antibody, produced in rabbits, is highly specific for human samples and is validated for use in applications such as Western blotting.PTPMT1 plays a crucial role in modulating cellular energy metabolism by dephosphorylating phosphatidylinositol phosphates in the inner mitochondrial membrane. Dysregulation of PTPMT1 has been implicated in various diseases, including metabolic disorders and cancer.
Therefore, understanding the function of PTPMT1 is essential for uncovering potential therapeutic targets in these pathological conditions.With its high specificity and sensitivity, the PTPMT1 Polyclonal Antibody (CAB8594) enables researchers to accurately detect and analyze PTPMT1 protein levels in various cell types. This makes it an indispensable tool for studies in mitochondrial biology, metabolism, and disease mechanisms related to PTPMT1 dysregulation.
Product Name:
PTPMT1 Rabbit Polyclonal Antibody
SKU:
CAB8594
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-201 of human PTPMT1 (NP_783859.1).
Predicted to enable phosphatidylglycerophosphatase activity and phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity. Involved in regulation of intrinsic apoptotic signaling pathway. Located in mitochondrion.
Purification Method:
Affinity purification
Gene ID:
114971
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of mouse heart, using PTPMT1 Antibody (CAB8594) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 20s.
