The PTP4A3 Polyclonal Antibody (CAB2004) is a powerful tool for researchers studying PTP4A3, a protein involved in cell signaling pathways and cancer progression. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to PTP4A3, this antibody allows for the detection and analysis of the protein in various cell types, making it a valuable asset for studies in cancer biology and signaling research.PTP4A3, also known as protein tyrosine phosphatase type IVA, is known to play a crucial role in promoting cell proliferation, migration, and invasion in cancer cells.
Its dysregulation has been linked to various types of cancers, making it an attractive target for therapeutic interventions. By understanding the function of PTP4A3, researchers can design targeted therapies to inhibit its activity and potentially slow down cancer progression.Overall, the PTP4A3 Polyclonal Antibody (CAB2004) is a reliable tool for researchers looking to unravel the role of PTP4A3 in cancer biology and cell signaling pathways. Its specificity and sensitivity make it a valuable asset for studies aiming to elucidate the mechanisms underlying cancer progression and identify new therapeutic targets for cancer treatment.
Product Name:
PTP4A3 Rabbit Polyclonal Antibody
SKU:
CAB2004
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-148 of human PTP4A3 (NP_009010.2).
This gene encodes a member of the protein-tyrosine phosphatase family. Protein tyrosine phosphatases are cell signaling molecules that play regulatory roles in a variety of cellular processes. Studies of this class of protein tyrosine phosphatase in mice demonstrates that they are prenylated in vivo, suggesting their association with cell plasma membrane. The encoded protein may enhance cell proliferation, and overexpression of this gene has been implicated in tumor metastasis. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
11156
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse skeletal muscle, using PTP4A3 Rabbit pAb (CAB2004) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).
