PTP4A2 Rabbit Polyclonal Antibody (CAB15335)
- SKU:
- CAB15335
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | PTP4A2 Rabbit Polyclonal Antibody |
SKU: | CAB15335 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-100 of human PTP4A2 (NP_536316.1). |
Sequence: | FTEE LKKY GVTT LVRV CDAT YDKA PVEK EGIH VLDW PFDD GAPP PNQI VDDW LNLL KTKF REEP GCCV AVH |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:200 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | HH13; OV-1; PRL2; HH7-2; PRL-2; PTP4A; HU-PP-1; PTPCAAX2; ptp-IV1a; ptp-IV1b; PTP4A2 |
Positive Sample: | MCF7,Mouse skeletal muscle,Mouse brain,Mouse kidney,Mouse liver,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Early endosome. |
Calculated MW: | 19kDa |
Observed MW: | 19kDa |
The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17.
Purification Method: | Affinity purification |
Gene ID: | 8073 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |