The PTOV1 Polyclonal Antibody (CAB16126) is a valuable tool for researchers studying the PTOV1 protein, which is known for its role in cancer progression and metastasis. This antibody, generated in rabbits, exhibits high specificity and sensitivity for detecting PTOV1 in human samples, making it an ideal choice for Western blot applications.PTOV1 is a transcriptional regulator that has been implicated in the development and progression of various types of cancer, including prostate and breast cancer. Its overexpression has been linked to tumor growth, invasion, and resistance to therapy, highlighting its potential as a therapeutic target.
By using the PTOV1 Polyclonal Antibody, researchers can gain valuable insights into the function and regulation of PTOV1 in cancer biology. This antibody enables the detection and analysis of PTOV1 protein levels in different cell types, providing a deeper understanding of its role in tumorigenesis. Ultimately, studies using this antibody may contribute to the development of novel strategies for diagnosing and treating cancer.
Product Name:
PTOV1 Rabbit Polyclonal Antibody
SKU:
CAB16126
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PTOV1 (NP_001292037.1).
Cell membrane, Cytoplasm, Nucleus, perinuclear region
Calculated MW:
47kDa
Observed MW:
47kDa
This gene encodes a protein that was found to be overexpressed in prostate adenocarcinomas. The encoded protein was found to interact with the lipid raft protein flotillin-1 and shuttle it from the cytoplasm to the nucleus in a cell cycle dependent manner. Alternative splicing of this gene results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
53635
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from HT-29 cells, using PTOV1 Rabbit pAb (CAB16126) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
