The PTN Polyclonal Antibody (CAB3124) is a research tool designed for studying the PTN protein, which plays a crucial role in various biological processes including cell growth, angiogenesis, and neuroprotection. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in applications such as Western blotting.PTN, also known as pleiotrophin, is a secreted signaling molecule that is implicated in the regulation of cell proliferation and differentiation. It has been linked to cancer progression, neurodegenerative diseases, and wound healing processes. The PTN Polyclonal Antibody binds specifically to the PTN protein, allowing for its detection and analysis in a wide range of cell types.
Research involving PTN is important for understanding its role in various physiological and pathological conditions, and may lead to the development of novel therapeutic strategies for treating diseases such as cancer and neurodegenerative disorders. By utilizing the PTN Polyclonal Antibody, researchers can gain valuable insights into the function and regulation of PTN, advancing our knowledge of the molecular mechanisms underlying these complex biological processes.
Product Name:
PTN Rabbit Polyclonal Antibody
SKU:
CAB3124
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-50 of human PTN (P21246).
The protein encoded by this gene is a secreted heparin-binding growth factor. The protein has significant roles in cell growth and survival, cell migration, angiogenesis and tumorigenesis. Alternative splicing and the use of alternative promoters results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
5764
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PTN Rabbit pAb (CAB3124) at 1:400 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 60s.
