The PTMA Polyclonal Antibody (PACO18981) is a valuable tool for researching PTMA, a protein involved in various cellular processes, including cell proliferation and differentiation. This antibody, derived from rabbit hosts, is highly specific for detecting PTMA in human samples and has been validated for use in Western blot experiments. By binding to PTMA, this antibody enables researchers to investigate the role of PTMA in different cell types, providing insights into its function and potential implications in disease mechanisms.
PTMA, also known as prothymosin alpha, has been linked to various diseases, including cancer and autoimmune disorders. By studying PTMA's function and expression levels, researchers can gain a better understanding of its involvement in disease progression and potentially identify new therapeutic targets. The PTMA Polyclonal Antibody is a valuable tool for advancing research in the fields of oncology and immunology, shedding light on the role of PTMA in health and disease.
Antibody Name:
PTMA Antibody (PACO18981)
Antibody SKU:
PACO18981
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Synthetic peptide of human PTMA
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO18981(PTMA Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human lymphoma tissue using PACO18981(PTMA Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
Prothymosin α may mediate immune function by conferring resistance to certain opportunistic infections and as oncogenes contributing to cell proliferation and invasion in BC. Silencing of these gene significantly inhibited cell proliferation and invasion, and increased apoptosis in BC cells. Immunohistochemistry showed that PTMA expression levels were significantly higher in BC compared to normal bladder epitheliums.
Synonyms:
prothymosin, alpha
UniProt Protein Function:
PTMA: Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections. Belongs to the pro/parathymosin family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:
Protein type:Cell cycle regulation; Nuclear receptor co-regulator
