The PTK7 Polyclonal Antibody (CAB9839) is a valuable tool for researchers studying the PTK7 protein, a receptor tyrosine kinase involved in various cellular processes such as cell proliferation, differentiation, and migration. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By targeting the PTK7 protein, this antibody enables researchers to detect and analyze PTK7 expression in different cell types, making it well-suited for investigations in cancer biology and developmental biology.PTK7 plays a crucial role in cell signaling pathways and has been implicated in tumorigenesis, making it a promising target for cancer therapy research.
Understanding the functions and mechanisms of PTK7 can provide insights into its potential as a therapeutic target for cancer treatment. Additionally, PTK7 has been linked to developmental processes such as neural tube closure and tissue morphogenesis, highlighting its importance in embryonic development and tissue homeostasis. By using the PTK7 Polyclonal Antibody, researchers can further explore the roles of PTK7 in both normal and disease conditions, ultimately advancing our understanding of its biological functions and potential clinical applications.
Product Name:
PTK7 Rabbit Polyclonal Antibody
SKU:
CAB9839
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 811-1070 of human PTK7 (NP_002812.2).
Cell junction, Membrane, Single-pass type I membrane protein.
Calculated MW:
118kDa
Observed MW:
160kDa
This gene encodes a member of the receptor protein tyrosine kinase family of proteins that transduce extracellular signals across the cell membrane. The encoded protein lacks detectable catalytic tyrosine kinase activity, is involved in the Wnt signaling pathway and plays a role in multiple cellular processes including polarity and adhesion. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
5754
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using PTK7 Rabbit pAb (CAB9839) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
