The PTK2 Polyclonal Antibody (CAB11195) offered by Assay Genie is a powerful tool for researchers studying the PTK2 protein, also known as FAK (Focal Adhesion Kinase). This antibody is raised in rabbits and demonstrates high reactivity with human samples, making it an ideal choice for Western blot applications.PTK2 is a critical regulator of cell adhesion, migration, and signaling pathways involved in cancer progression and metastasis. By binding specifically to the PTK2 protein, this antibody enables researchers to detect and analyze PTK2 expression in a variety of cell types.
This makes it particularly valuable for investigations in cancer biology and drug development.Targeting PTK2 holds promise for developing novel cancer therapies that disrupt tumor growth and metastasis. The PTK2 Polyclonal Antibody from Assay Genie provides researchers with a reliable tool to further explore the role of PTK2 in cancer biology and identify potential targets for intervention.
Product Name:
FAK Rabbit Polyclonal Antibody
SKU:
CAB11195
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 734-834 of human FAK (NP_722560.1).
This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
5747
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using FAK Rabbit pAb (CAB11195) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
