The PTK2 Monoclonal Antibody (CAB11131) is a valuable tool for researchers studying PTK2, a protein kinase involved in cell adhesion, migration, and signaling processes. This antibody, produced through monoclonal antibody technology, specifically targets PTK2 in human samples and is suitable for use in Western blot and immunohistochemistry applications. PTK2, also known as focal adhesion kinase (FAK), plays a crucial role in mediating cell-cell and cell-matrix interactions, making it a key player in cancer metastasis, wound healing, and tissue development.
By targeting PTK2 with this antibody, researchers can gain insights into the mechanisms by which PTK2 regulates cellular behavior and potentially identify new therapeutic targets for treating diseases associated with abnormal cell adhesion and migration. Given the importance of PTK2 in various physiological and pathological processes, the PTK2 Monoclonal Antibody (CAB11131) is a valuable tool for advancing research in cell biology, cancer biology, and drug discovery.
Product Name:
FAK Rabbit Monoclonal Antibody
SKU:
CAB11131
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 700-800 of human FAK (Q05397).
This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
5747
Clone Number:
ARC0171
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using FAK pAb (CAB11131) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
