PTHLH Rabbit Polyclonal Antibody (CAB3183)
- SKU:
- CAB3183
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PTHLH Rabbit Polyclonal Antibody |
SKU: | CAB3183 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-175 of human PTHLH (NP_945316.1). |
Sequence: | GRSV EGLS RRLK RAVS EHQL LHDK GKSI QDLR RRFF LHHL IAEI HTAE IRAT SEVS PNSK PSPN TKNH PVRF GSDD EGRY LTQE TNKV ETYK EQPL KTPG KKKK GKPG KRKE QEKK KRRT RSAW LDSG VTGS GLEG DHLS DTST TSLE LDSR |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:2000 - 1:9000 |
Synonyms: | HHM; PLP; BDE2; PTHR; PTHRP; PTHLH |
Positive Sample: | PC-3,U-251MG |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, Secreted. |
Calculated MW: | 20kDa |
Observed MW: | 20kDa |
The protein encoded by this gene is a member of the parathyroid hormone family. This hormone, via its receptor, PTHR1, regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. It is responsible for most cases of humoral hypercalcemia of malignancy, and mutations in this gene are associated with brachydactyly type E2 (BDE2). Alternatively spliced transcript variants have been found for this gene. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, downstream of the initiator AUG codon, resulting in nuclear forms of this hormone.
Purification Method: | Affinity purification |
Gene ID: | 5744 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |