PTH1R Rabbit Polyclonal Antibody (CAB1744)
- SKU:
- CAB1744
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PTH1R Rabbit Polyclonal Antibody |
SKU: | CAB1744 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 27-188 of human PTH1R (NP_000307.1). |
Sequence: | DADD VMTK EEQI FLLH RAQA QCEK RLKE VLQR PASI MESD KGWT SAST SGKP RKDK ASGK LYPE SEED KEAP TGSR YRGR PCLP EWDH ILCW PLGA PGEV VAVP CPDY IYDF NHKG HAYR RCDR NGSW ELVP GHNR TWAN YSEC VKFL TNET RERE VFDR LG |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | PFE; EKNS; PTHR; PTHR1; PTH1R |
Positive Sample: | Jurkat,MCF7,U-251MG,DU145,THP-1,Mouse kidney,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Multi-pass membrane protein. |
Calculated MW: | 66kDa |
Observed MW: | 66kDa |
The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 5745 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |