COX1/PTGS1 Rabbit Polyclonal Antibody (CAB7341)
- SKU:
- CAB7341
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | COX1/PTGS1 Rabbit Polyclonal Antibody |
SKU: | CAB7341 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human COX1/COX1/PTGS1 (NP_001258094.1). |
Sequence: | MLMR LVLT VRSN LIPS PPTY NSAH DYIS WESF SNVS YYTR ILPS VPKD CPTP MGTK GKKQ LPDA QLLA RRFL LRRK FIPD PQGT NLMF AFFA QHFT HQFF KTSG KMGP GFTK ALGH GVDL GHIY GDNL ERQY QLRL FKDG KLKY QVLD GEMY PPSV EEAP VLMH YPRG IPPQ SQMA VGQE |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:100 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | COX1; COX3; PHS1; PCOX1; PES-1; PGHS1; PTGHS; PGG/HS; PGHS-1; COX1/PTGS1 |
Positive Sample: | HL-60,A-549,HT-29,THP-1,Mouse lung,Mouse liver,Mouse kidney,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum membrane, Microsome membrane, Peripheral membrane protein. |
Calculated MW: | 69kDa |
Observed MW: | 69kDa |
This is one of two genes encoding similar enzymes that catalyze the conversion of arachidonate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 5742 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |