COX1/PTGS1 Rabbit Monoclonal Antibody (CAB4301)
- SKU:
- CAB4301
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | COX1/PTGS1 Rabbit Monoclonal Antibody |
SKU: | CAB4301 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human COX1/PTGS1 (P23219). |
Sequence: | GLDR YQCD CTRT GYSG PNCT IPGL WTWL RNSL RPSP SFTH FLLT HGRW FWEF VNAT FIRE MLMR LVLT VRSN LIPS PPTY NSAH DYIS WESF SNVS YYTR I |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | COX1; COX3; PHS1; PCOX1; PES-1; PGHS1; PTGHS; PGG/HS; PGHS-1; COX1/PTGS1 |
Positive Sample: | HeLa,Mouse lung,Mouse liver,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum membrane, Microsome membrane, Peripheral membrane protein. |
Calculated MW: | 69kDa |
Observed MW: | 65kDa/72kDa |
This is one of two genes encoding similar enzymes that catalyze the conversion of arachidonate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 5742 |
Clone Number: | ARC0960 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |