The PTGIR Polyclonal Antibody (CAB1849) is a valuable tool for researchers studying the prostaglandin I2 receptor (PTGIR), a key player in inflammation and cardiovascular disease. This antibody, generated in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the PTGIR protein, this antibody allows for accurate detection and analysis in various cell types, making it an essential component for studies in pharmacology and cardiovascular research.The PTGIR receptor, also known as prostacyclin receptor, is involved in mediating vasodilation and inhibiting platelet aggregation, making it a crucial target for understanding cardiovascular health and inflammation regulation.
Dysregulation of PTGIR signaling has been implicated in various cardiovascular diseases, making it a promising area of research for developing new therapeutic strategies. By utilizing the PTGIR Polyclonal Antibody, researchers can gain valuable insights into the mechanisms underlying cardiovascular disease and inflammation, ultimately leading to the development of novel treatment options.
Product Name:
PTGIR Rabbit Polyclonal Antibody
SKU:
CAB1849
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 207-386 of human PTGIR (NP_000951.1).
The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor.
Purification Method:
Affinity purification
Gene ID:
5739
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using PTGIR Rabbit pAb (CAB1849) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
