The PTGFRN Polyclonal Antibody (PACO06919) is a crucial tool for researchers studying PTGFRN, a protein involved in cell signaling pathways and inflammatory responses. This antibody, produced in rabbits, exhibits high specificity and reactivity with human samples, making it an ideal choice for Western blot applications. By binding to PTGFRN, researchers can accurately detect and analyze this protein in a variety of cell types, facilitating investigations in immunology, inflammation, and cancer research.PTGFRN, also known as prostaglandin F2 receptor negative regulator, serves as a key regulator of prostaglandin signaling, impacting processes such as cell proliferation, migration, and inflammation.
Its role in modulating inflammatory responses implicates PTGFRN in various diseases, including cancer, cardiovascular disorders, and inflammatory conditions. Uncovering the functions of PTGFRN is essential for advancing our understanding of inflammatory pathways and developing targeted therapies for related diseases.
Antibody Name:
PTGFRN Antibody (PACO06919)
Antibody SKU:
PACO06919
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:10000, WB:1:500-1:2000
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Synthesized peptide derived from the Internal region of human CD315.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:200.
Western Blot analysis of 293 cells using CD315 Polyclonal Antibody.
PTGFRN: Inhibits the binding of prostaglandin F2-alpha (PGF2- alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. Functional coupling with the prostaglandin F2-alpha receptor seems to occur.Protein type: Cytoskeletal; Membrane protein, integralChromosomal Location of Human Ortholog: 1p13.1Cellular Component: cell surfaceMolecular Function: protein binding
