The PTGES3 Polyclonal Antibody (CAB5325) is a valuable tool for researchers studying the PTGES3 protein, also known as prostaglandin E synthase 3. This antibody, raised in rabbits, is specifically designed for use in Western blot applications and is highly reactive with human samples.PTGES3 is an enzyme involved in the production of prostaglandin E2 (PGE2), a key mediator of inflammation and pain. The ability to detect and quantify PTGES3 protein levels in various cell types is essential for understanding its role in inflammatory responses and developing targeted therapies for conditions such as arthritis, cancer, and fibrosis.
By using the PTGES3 Polyclonal Antibody, researchers can accurately measure PTGES3 expression in cell lysates, tissue samples, and other biological samples. This antibody is a valuable tool for studies investigating the regulatory mechanisms of PGE2 production and its impact on inflammatory processes.
Product Name:
P23/PTGES3 Rabbit Polyclonal Antibody
SKU:
CAB5325
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human P23/P23/PTGES3 (NP_006592.3).
This gene encodes an enzyme that converts prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). This protein functions as a co-chaperone with heat shock protein 90 (HSP90), localizing to response elements in DNA and disrupting transcriptional activation complexes. Alternative splicing results in multiple transcript variants. There are multiple pseudogenes of this gene on several different chromosomes.
Purification Method:
Affinity purification
Gene ID:
10728
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using P23/PTGES3 Rabbit pAb (CAB5325) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
