The PTGES3 Polyclonal Antibody (CAB13399) is a valuable tool for researchers studying the PTGES3 protein, which plays a crucial role in the synthesis of prostaglandin E2 (PGE2), an important mediator of inflammation and immune responses. This antibody, generated from rabbits, has high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to PTGES3, researchers can easily detect and analyze the protein in a variety of cell types, making it ideal for studies in immunology, inflammation, and cancer research.
PTGES3 is a key enzyme in the production of PGE2, which has diverse effects on immune cells and plays a role in both acute and chronic inflammatory processes. Understanding the function of PTGES3 is essential for uncovering its potential as a therapeutic target in diseases such as cancer, autoimmune disorders, and inflammatory conditions. Research utilizing the PTGES3 Polyclonal Antibody can provide valuable insights into the role of PGE2 in immune regulation and pave the way for the development of novel treatments targeting the PTGES3 pathway.
Product Name:
P23/PTGES3 Rabbit Polyclonal Antibody
SKU:
CAB13399
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human P23/P23/PTGES3 (NP_006592.3).
This gene encodes an enzyme that converts prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). This protein functions as a co-chaperone with heat shock protein 90 (HSP90), localizing to response elements in DNA and disrupting transcriptional activation complexes. Alternative splicing results in multiple transcript variants. There are multiple pseudogenes of this gene on several different chromosomes.
Purification Method:
Affinity purification
Gene ID:
10728
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma using P23/PTGES3 Rabbit pAb (CAB13399) at dilution of 1:200 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
