The PTGES Polyclonal Antibody (CAB18632) is a valuable tool for research involving the PTGES protein, which plays a crucial role in prostaglandin E2 synthesis and inflammatory responses. This antibody, derived from rabbits, is highly specific and reacts strongly with human samples. It has been validated for use in Western blot applications, enabling the detection and analysis of PTGES in a variety of cell types.PTGES, also known as prostaglandin E synthase, is involved in the production of prostaglandin E2, a key player in inflammation and immune responses.
Understanding the function of PTGES is essential for research in areas such as immunology, cancer, and inflammatory diseases. By targeting PTGES, researchers can gain insight into the mechanisms underlying these conditions and potentially develop new therapeutic strategies.Overall, the PTGES Polyclonal Antibody (CAB18632) is a reliable tool for studying the role of PTGES in various biological processes, offering researchers a valuable resource in their investigations into inflammation, immunity, and disease.
Product Name:
PTGES Rabbit Polyclonal Antibody
SKU:
CAB18632
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PTGES (NP_004869.1).
The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses.
Purification Method:
Affinity purification
Gene ID:
9536
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from MCF7 cells, using PTGES Rabbit pAb (CAB18632) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
