The PTGER3 Polyclonal Antibody (CAB4057) is a valuable tool for researchers studying the PTGER3 protein, a member of the prostaglandin E receptor family involved in various physiological processes, including inflammation, immune response, and cancer progression. This antibody is generated in rabbits and exhibits high reactivity with human samples, making it suitable for use in Western blot applications for the detection and analysis of PTGER3 protein levels.PTGER3, also known as EP3, is known to play a crucial role in mediating the effects of prostaglandin E2 (PGE2) on cells, influencing signal transduction pathways that regulate cell proliferation, differentiation, and apoptosis. Dysregulation of PTGER3 signaling has been implicated in various diseases, including inflammation-related disorders, cancer, and gastrointestinal diseases.
Therefore, studying the function and expression of PTGER3 is instrumental in understanding its role in disease pathogenesis and identifying potential therapeutic targets.By using the PTGER3 Polyclonal Antibody (CAB4057), researchers can gain valuable insights into PTGER3 expression patterns and its impact on cellular processes, paving the way for the development of novel treatment strategies for diseases associated with dysregulated PTGER3 signaling. Its specificity and reliability make it an indispensable tool for studies focused on unraveling the complex biology of PTGER3 in health and disease.
The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor may have many biological functions, which involve digestion, nervous system, kidney reabsorption, and uterine contraction activities. Studies of the mouse counterpart suggest that this receptor may also mediate adrenocorticotropic hormone response as well as fever generation in response to exogenous and endogenous stimuli. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
5733
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PGE receptor EP3 (PTGER3) Rabbit pAb (CAB4057) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
