PTGDS Rabbit Polyclonal Antibody (CAB1889)
- SKU:
- CAB1889
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | PTGDS Rabbit Polyclonal Antibody |
SKU: | CAB1889 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 23-190 of human PTGDS (NP_000945.3). |
Sequence: | APEA QVSV QPNF QQDK FLGR WFSA GLAS NSSW LREK KAAL SMCK SVVA PATD GGLN LTST FLRK NQCE TRTM LLQP AGSL GSYS YRSP HWGS TYSV SVVE TDYD QYAL LYSQ GSKG PGED FRMA TLYS RTQT PRAE LKEK FTAF CKAQ GFTE DTIV FLPQ TDKC MTEQ |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IF/ICC,1:50 - 1:100 |
Synonyms: | PDS; PGD2; PGDS; LPGDS; PGDS2; L-PGDS; PTGDS |
Positive Sample: | Mouse heart |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Golgi apparatus, Nucleus membrane, Rough endoplasmic reticulum, Secreted, perinuclear region. |
Calculated MW: | 21kDa |
Observed MW: | 28kDa |
The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep.
Purification Method: | Affinity purification |
Gene ID: | 5730 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |