The PTGDS Polyclonal Antibody (CAB1889) is a valuable tool for researchers studying PTGDS, a protein involved in various biological processes such as lipid metabolism, inflammation, and immune regulation. This rabbit-raised antibody exhibits high reactivity with human samples and has been validated for use in Western blot applications.PTGDS, also known as prostaglandin D2 synthase, plays a crucial role in the biosynthesis of prostaglandin D2, a lipid mediator involved in allergic reactions, sleep regulation, and inflammation. By targeting PTGDS, researchers can gain insights into its physiological functions and explore potential therapeutic interventions for conditions related to lipid metabolism and inflammation.
With its ability to bind specifically to PTGDS protein, this polyclonal antibody enables accurate detection and analysis in various cell types, making it an ideal tool for studies in immunology, lipid metabolism, and inflammatory diseases. By understanding the role of PTGDS in these processes, researchers can develop novel strategies for managing conditions associated with dysregulated lipid metabolism and inflammation.
Product Name:
PTGDS Rabbit Polyclonal Antibody
SKU:
CAB1889
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 23-190 of human PTGDS (NP_000945.3).
The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep.
Purification Method:
Affinity purification
Gene ID:
5730
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of Mouse heart, using PTGDS antibody (CAB1889) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
