The PTCRA Polyclonal Antibody (CAB7150) is a valuable tool for researchers studying the PTCRA gene, which is involved in T cell development and activation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the PTCRA protein, researchers can effectively detect and analyze its expression in various cell types, providing valuable insights into the role of PTCRA in immune function.The PTCRA gene, also known as pre T-cell antigen receptor alpha, is essential for the development and maturation of T cells, which play a critical role in adaptive immunity.
Dysregulation of PTCRA expression has been implicated in various diseases, including autoimmune disorders and leukemia. Therefore, studying the function of PTCRA with the help of this antibody is crucial for understanding its role in immune system regulation and disease pathogenesis.Overall, the PTCRA Polyclonal Antibody (CAB7150) is a powerful tool for researchers interested in unraveling the complexities of T cell biology and its implications for human health. Its specificity and reliability make it an ideal choice for studies in immunology, cancer research, and beyond.
Product Name:
PTCRA Rabbit Polyclonal Antibody
SKU:
CAB7150
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 172-281 of human PTCRA (NP_612153.2).
The protein encoded by this gene is a single-pass type I membrane protein that is found in immmature but not mature T-cells. Along with TCRB and CD3 complex, the encoded protein forms the pre-T-cell receptor complex, which regulates early T-cell development. Four transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
171558
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PTCRA antibody (CAB7150) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
