The PTCD3 Polyclonal Antibody (CAB8497) is a valuable tool for researchers studying PTCD3, a protein involved in mitochondrial RNA processing and maturation. This antibody, raised in rabbits, exhibits high specificity and sensitivity towards PTCD3 in human samples, making it a reliable choice for Western blot applications. By binding to PTCD3, this antibody allows for the detection and analysis of the protein in various cell types, facilitating research into mitochondrial gene expression and RNA metabolism.
PTCD3 is essential for proper mitochondrial function, as it plays a crucial role in the processing of mitochondrial RNA molecules. Dysregulation of PTCD3 has been associated with defects in mitochondrial RNA processing and maturation, leading to mitochondrial dysfunction and diseases such as mitochondrial myopathies. Therefore, studying PTCD3 using this polyclonal antibody may provide insights into the mechanisms underlying these conditions and offer potential targets for therapeutic interventions.
Product Name:
PTCD3 Rabbit Polyclonal Antibody
SKU:
CAB8497
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 450-689 of human PTCD3 (NP_060422.4).
Enables rRNA binding activity and ribosomal small subunit binding activity. Involved in mitochondrial translation. Located in several cellular components, including cytosol; mitochondrion; and nucleoplasm. Implicated in combined oxidative phosphorylation deficiency 51.
Purification Method:
Affinity purification
Gene ID:
55037
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PTCD3 antibody (CAB8497) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
