The PTCD1 Polyclonal Antibody (CAB16219) is a valuable tool for researching PTCD1, a protein associated with mitochondrial RNA processing. This antibody, produced in rabbits, exhibits high reactivity with human samples and is specifically validated for use in Western blot applications. By binding to the PTCD1 protein, this antibody enables accurate detection and analysis in various cell types, making it a versatile option for studies in molecular biology and mitochondrial research.PTCD1 is essential for the proper functioning of mitochondria, the powerhouse of the cell, and plays a crucial role in RNA metabolism within this organelle.
Dysregulation of PTCD1 has been linked to mitochondrial dysfunction and cellular damage, making it a potential target for investigating diseases like metabolic disorders, neurodegenerative diseases, and cancer. Research into the function and regulation of PTCD1 is vital for advancing our understanding of mitochondrial biology and developing targeted therapies for related conditions.
Product Name:
PTCD1 Rabbit Polyclonal Antibody
SKU:
CAB16219
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 435-537 of human PTCD1 (NP_056360.2).
This gene encodes a mitochondrial protein that binds leucine tRNAs and other mitochondrial RNAs and plays a role in the regulation of translation. Increased expression of this gene results in decreased mitochondrial leucine tRNA levels. Naturally occurring read-through transcription exists between upstream ATP5J2 (ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2) and this gene.
Purification Method:
Affinity purification
Gene ID:
26024
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PTCD1 Rabbit pAb (CAB16219) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
