UniProt Protein Function: | ROD1: RNA-binding protein that mediates pre-mRNA alternative splicing regulation. Plays a role in the regulation of cell proliferation, differentiation and migration. Positive regulator of EPO-dependent erythropoiesis. Participates in cell differentiation regulation by repressing tissue-specific exons. Promotes FAS exon 6 skipping. Binds RNA, preferentially to both poly(G) and poly(U). 6 isoforms of the human protein are produced by alternative splicing.Protein type: RNA-bindingChromosomal Location of Human Ortholog: 9q32Molecular Function: RNA bindingBiological Process: anatomical structure morphogenesis; negative regulation of RNA splicing |
UniProt Protein Details: | |
NCBI Summary: | The protein encoded by this gene binds RNA and is a regulator of cell differentiation. The encoded protein preferentially binds to poly(G) and poly(U) sequences in vitro. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] |
UniProt Code: | O95758 |
NCBI GenInfo Identifier: | 218511814 |
NCBI Gene ID: | 9991 |
NCBI Accession: | O95758.2 |
UniProt Secondary Accession: | O95758,Q68DB9, Q86YB3, Q86YH9, B1ALY2, B1ALY3, B1ALY5 B1ALY6, B3KME7 |
UniProt Related Accession: | O95758 |
Molecular Weight: | 49,540 Da |
NCBI Full Name: | Polypyrimidine tract-binding protein 3 |
NCBI Synonym Full Names: | polypyrimidine tract binding protein 3 |
NCBI Official Symbol: | PTBP3Â Â |
NCBI Official Synonym Symbols: | ROD1Â Â |
NCBI Protein Information: | polypyrimidine tract-binding protein 3 |
UniProt Protein Name: | Polypyrimidine tract-binding protein 3 |
UniProt Synonym Protein Names: | Regulator of differentiation 1; Rod1 |
Protein Family: | Polypyrimidine tract-binding protein |
UniProt Gene Name: | PTBP3Â Â |
UniProt Entry Name: | PTBP3_HUMAN |