The PTBP3 Polyclonal Antibody (PAC011886) is a valuable tool for researchers studying PTBP3, a protein involved in RNA processing and regulation. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to PTBP3, this antibody allows for accurate detection and analysis of PTBP3 expression in a variety of cell types, making it an excellent choice for studies in molecular biology and cancer research.PTBP3, also known as polypyrimidine tract-binding protein 3, plays a crucial role in modulating RNA splicing and stability, making it a key player in gene expression regulation.
Its involvement in various cellular processes highlights its relevance in diseases such as cancer, neurodegenerative disorders, and metabolic diseases. By investigating the function of PTBP3, researchers can gain insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets for intervention.
ROD1 regulator of differentiation 1 (S. pombe);ROD1;DKFZp781I1117;PTBP3 ;
UniProt Protein Function:
ROD1: RNA-binding protein that mediates pre-mRNA alternative splicing regulation. Plays a role in the regulation of cell proliferation, differentiation and migration. Positive regulator of EPO-dependent erythropoiesis. Participates in cell differentiation regulation by repressing tissue-specific exons. Promotes FAS exon 6 skipping. Binds RNA, preferentially to both poly(G) and poly(U). 6 isoforms of the human protein are produced by alternative splicing.Protein type: RNA-bindingChromosomal Location of Human Ortholog: 9q32Molecular Function: RNA bindingBiological Process: anatomical structure morphogenesis; negative regulation of RNA splicing
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene binds RNA and is a regulator of cell differentiation. The encoded protein preferentially binds to poly(G) and poly(U) sequences in vitro. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
