The PTBP2 Polyclonal Antibody (CAB6054) is a valuable tool for researchers studying the PTBP2 protein, which is involved in regulating alternative splicing of pre-mRNA in cells. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in various applications, including Western blotting.PTBP2, also known as polypyrimidine tract-binding protein 2, plays a crucial role in the control of gene expression by influencing RNA processing and splicing mechanisms. Dysregulation of PTBP2 has been linked to various diseases, including cancer and neurological disorders, making it an important target for further investigation.
By using the PTBP2 Polyclonal Antibody, researchers can detect and analyze PTBP2 expression levels in different cell types, providing valuable insights into its function and potential therapeutic implications. This antibody is a valuable tool for studies in molecular biology, RNA processing, and disease mechanisms, helping to advance our understanding of PTBP2 and its role in health and disease.
Product Name:
PTBP2 Rabbit Polyclonal Antibody
SKU:
CAB6054
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human PTBP2 (NP_001287918.1).
The protein encoded by this gene binds to intronic polypyrimidine clusters in pre-mRNA molecules and is implicated in controlling the assembly of other splicing-regulatory proteins. This protein is very similar to the polypyrimidine tract binding protein (PTB) but most of its isoforms are expressed primarily in the brain. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
58155
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat testis, using PTBP2 Rabbit pAb (CAB6054) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
