PSMF1 Rabbit Polyclonal Antibody (CAB5554)
- SKU:
- CAB5554
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | PSMF1 Rabbit Polyclonal Antibody |
SKU: | CAB5554 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-271 of human PSMF1 (NP_006805.2). |
Sequence: | MAGL EVLF ASAA PAIT CRQD ALVC FLHW EVVT HGYF GLGV GDQP GPND KKSE LLPA GWNN NKDL YVLR YEYK DGSR KLLV KAIT VESS MILN VLEY GSQQ VADL TLNL DDYI DAEH LGDF HRTY KNSE ELRS RIVS GIIT PIHE QWEK ANVS SPHR EFPP ATAR EVDP LRIP PHHP HTSR QPPW CDPL GPFV VGGE DLDP FGPR RGGM IVDP LRSG FPRA LIDP SSGL PNRL PPGA VPPG ARFD PFGP IGTS PPGP NPDH LPPP GYDD MYL |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | PI31; PSMF1 |
Positive Sample: | Jurkat,HepG2,HeLa,Mouse testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Endoplasmic reticulum. |
Calculated MW: | 30kDa |
Observed MW: | 30kDa |
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a protein that inhibits the activation of the proteasome by the 11S and 19S regulators. Alternative transcript variants have been identified for this gene.
Purification Method: | Affinity purification |
Gene ID: | 9491 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |