null

PSME1 Monoclonal Antibody [PAT12H3AT] (CPAB0636)

SKU:
CPAB0636
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG2a
Clone:
PAT12H3AT
Applications:
WB
ELISA
$179

Description

system_update_alt Datasheet

PSME1 Monoclonal Antibody [PAT12H3AT] (CPAB0636)

The PSME1 Polyclonal Antibody (CPAB0636) is a valuable tool for researchers studying the proteasome activator complex subunit 1 (PSME1). PSME1 is essential for the activation of the 20S proteasome, a key player in protein degradation and regulation. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.By targeting PSME1, researchers can investigate the role of the proteasome activator complex in various cellular processes, including protein turnover, antigen processing, and cell cycle regulation.

Understanding the function of PSME1 is crucial for unraveling its involvement in diseases such as cancer, neurodegenerative disorders, and autoimmune conditions.With its high reactivity and specificity, the PSME1 Polyclonal Antibody is a reliable tool for research in cell biology, biochemistry, and drug discovery. Its ability to detect PSME1 protein in different cell types makes it a versatile option for studies aimed at uncovering the molecular mechanisms underlying protein degradation and cellular homeostasis.

Product Name:PSME1 Antibody
Product Sku:CPAB0636
Size:5μg
Host Species:Mouse
Immunogen:Anti-human PSME1 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PSME1 protein 1-249 amino acids purified from Ecoli.
Clone:PAT12H3AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:PSME1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2a
Background:PSME1 is an interferon gamma (IFNG) inducible proteasome activator essential for presentation of certain major histocompatibility (MHC) class I antigens. The PSME1 complex is an alternate proteasome activator which operates with no use of ubiquitin. The PSME1 complex is made out of two homologous subunits, alpha and beta, that functions in similar catalytic properties and is connected to a hexameric ring.
Synonyms:REG-alpha, PA28alpha, PA28a, Proteasome Activator subunit-1, Proteasome Activator 28 subunit alpha, Interferon gamma up-regulated I-5111 protein.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

Related Products