PSMD9 Rabbit Polyclonal Antibody (CAB5357)
- SKU:
- CAB5357
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | PSMD9 Rabbit Polyclonal Antibody |
SKU: | CAB5357 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-223 of human PSMD9 (NP_002804.2). |
Sequence: | MSDE EARQ SGGS SQAG VVTV SDVQ ELMR RKEE IEAQ IKAN YDVL ESQK GIGM NEPL VDCE GYPR SDVD LYQV RTAR HNII CLQN DHKA VMKQ VEEA LHQL HARD KEKQ ARDM AEAH KEAM SRKL GQSE SQGP PRAF AKVN SISP GSPA SIAG LQVD DEIV EFGS VNTQ NFQS LHNI GSVV QHSE GKPL NVTV IRRG EKHQ LRLV PTRW AGKG LLGC NIIP LQR |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | p27; Rpn4; PSMD9 |
Positive Sample: | H460,22Rv1,Jurkat,A-549 |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytosol, nucleoplasm, nucleus |
Calculated MW: | 25kDa |
Observed MW: | 25kDa |
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Three transcript variants encoding two different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 5715 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |